Everything about Sorangium Cellulosum totally explained
Sorangium cellulosum is a soil-dwelling
Gram-negative bacteria of the group
myxobacteria. It is motile and shows
gliding motility. It has an unusually-large genome 12,200,000 base pairs in size. A more recent work sequenced the genome of
Sorangium cellulosum So ce56 and put its size at 13033779 base pairs making it the largest bacterial genome sequenced to date.
Clinical use
Metabolites secreted by
Sorangium cellulosum known as
epothilones have been noted to have
antineoplastic activity. This has led to the development of
analogs which mimic its activity. One such analog, known as
Ixabepilone is a US
FDA approved chemotherapy agent for the treatment of
metastatic breast cancer.
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